Anorectics – Appetite Suppressants

Suppressors of appetite (Anorectic’s) they are also anorexigens and anorectics – a large class of sports nutrition and pharmacological drugs that reduce appetite, and thereby contribute to weight loss. Suppressors of appetite have various mechanisms of action, which are mainly aimed at suppressing the center of hunger and activating the center of satiety. 

In sports nutrition, anorectics are used very often in complex of fat burners. Almost all thermogenics are also appetite suppressants. 

Sports Nutrition – Anorectics: 

  • Lipovox; 
  • Phenphedrine; 
  • Adipozin; 
  • Testoripped; 
  • Colonoxy. 

 

Pharmacology 

The most effective and powerful appetite suppressants are pharmacological drugs. 

Anorectics affecting the serotonergic system: 

  • Fluoxetine is an inexpensive, safe, readily available and effective drug. The best choice. 
  • Sibutramine (Meridia) – a pronounced effect, but is pricey; 
  • Lorkaserin – a new serotonin receptor agonist; 
  • Denfluramine; 
  • Dexfenfluramine. 

Anorectics affecting the dopaminergic system: 

  • Bromocriptine; 
  • Cabergoline (Dostinex). 

Anorectics affecting the catecholaminergic system – inhibition of reuptake of norepinephrine, and, as a rule, stimulating the central nervous system: 

  • Amphetamine – Prohibited; 
  • Ampheramon (Fepranon) – Prohibited; 
  • Desopimon – Prohibited; 
  • Sibutramine (Meridia); 
  • Mazindol – Prohibited; 

Ephedrine and other adrenergic drugs can be attributed to the same class. 

Endogenous cannabinoid receptor blockers: 

  • Rimonabant; 

New studies have shown the beneficial effects of the antiepileptic drug Topiramate. 

 

Side Effects and Health Harm

Many anorectics are quite dangerous to health. For example, a drug such as Benfluorex is generally not recommended for use, as it can cause damage to heart valves and heart failure. 

Another fairly well-known drug, Fenfluramine, causes pulmonary hypertension, damage to heart valves, and myocardial fibrosis. Anorectics affecting the catecholamine system are simultaneously CNS stimulants; therefore, they are characterized by all side effects of the latter: agitation, insomnia, hyperactivity and so on. 

There are relatively safe anorectics, such as Fluoxetine and Sibutramine; in rare cases they cause pressure fluctuations, agitation, insomnia, etc. Sports nutrition does not meet with a pure anorexigenic effect, almost all appetite suppressants are thermo-geneticists, and side effects vary greatly depending from their composition.

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